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Methods: Data were pooled from three randomised, controlled clinical trials of epoetin beta in anaemic patients with solid tumours undergoing chemotherapy (ten Bokkel Huinink et al 1998; Oberhoff et al 1998; Boogaerts et al 2003).

To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.

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In 2002, Amgen revised package inserts for darbepoetin and Epogen to include recommendations that hemodialysis patients with antibody-mediated PRCA not be given other epoetins.

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Auerbach M, Ballard H, Trout JR et al (2004) Intravenous iron optimizes the response to recombinant human erythropoietin in cancer patients with chemotherapy-related anemia: a multicenter, open-label, randomized trial.

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Clinical Considerations and Practical Recommendations for the Primary Care Practitioner in the Management of Anemia of Chronic Kidney Disease.

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Nairz M, Schroll A, Moschen AR, Sonnweber T, Theurl M, Theurl I, Taub N, Jamnig C, Neurauter D, Huber LA, Tilg H, Moser PL, Weiss G (2011) Erythropoietin contrastingly affects bacterial infection and experimental colitis by inhibiting nuclear factor- κB-inducible immune pathways.

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Potassium and phosphate levels Serum potassium and phosphate concentrations should be monitored regularly during NEORECORMON therapy.

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This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.

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Shander A, Spence RK, Auerbach M (2010) Can intravenous iron therapy meet the unmet needs created by the new restrictions on erythropoietic stimulating agents?

FGF23 antagonism: the thin line between adaptation and maladaptation in chronic kidney disease.

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In short, all EPO products were applied to a stacking gel (5% polyacrylamide) and running gel (10% polyacrylamide).

If your hemoglobin level stays too high or goes up too quickly, this may lead to serious health problems which may result in death.

Rizzo JD, Lichtin AE, Woolf SH et al (2002) Use of epoetin in patients with cancer: evidence-based clinical practice guidelines of the American Society of Clinical Oncology and the American Society of Hematology.

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The court order was upheld on the grounds that the patient's refusal was open to doubt because it was potentially subject to outside influence (by co-religionists), and that where such doubt existed it should be resolved in favour of the preservation of life ().

The main conclusion from this comparative cost-efficiency analysis comparing biosimilar epoetin α with originator ESAs is that, for the EU G5, the cost of treating anemia in one patient with cancer during one line of chemotherapy (whether using fixed or weight-based dosing) is lowest for the biosimilar ESA, followed by originator epoetin α, epoetin β, darbepoetin α once weekly and finally darbepoetin α once every 3 weeks.

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Often, anemia exists in a milieu of chronic organ dysfunction or medical conditions that cloud the diagnosis because of their effect on erythropoiesis or red cell survival.

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